Leaders | Players | Teams | Award Races
| Pos | Player | Team | GP | G | A | Pts | +/- | PIM | PP | SH | GW | GT | Hits | Shots | % |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C | Sean Couturier | | 78 | 22 | 32 | 54 | -18 | 44 | 7 | 0 | 2 | 0 | 95 | 196 | 11.2 |
| C | Auston Matthews | | 76 | 26 | 27 | 53 | -1 | 10 | 5 | 1 | 3 | 0 | 192 | 172 | 15.1 |
| C | Brendan Brisson | | 74 | 29 | 24 | 53 | 23 | 39 | 2 | 1 | 4 | 1 | 139 | 197 | 14.7 |
| RW | Calle Jarnkork | | 77 | 28 | 25 | 53 | -7 | 0 | 2 | 0 | 6 | 0 | 92 | 173 | 16.2 |
| C | Connor McDavid | | 75 | 17 | 36 | 53 | 0 | 4 | 3 | 0 | 2 | 0 | 98 | 179 | 9.5 |
| RW | Jake Virtanen | | 76 | 18 | 35 | 53 | 17 | 49 | 2 | 0 | 6 | 0 | 130 | 192 | 9.4 |
| C | Tage Thompson | | 74 | 14 | 39 | 53 | 0 | 40 | 3 | 0 | 1 | 0 | 126 | 217 | 6.5 |
| LW | Trent Frederic | | 76 | 18 | 35 | 53 | 1 | 24 | 5 | 0 | 3 | 0 | 136 | 177 | 10.2 |
| C | Trevor Zegras | | 75 | 25 | 28 | 53 | -4 | 36 | 4 | 0 | 4 | 1 | 153 | 173 | 14.5 |
| LW | Alexis Lafreniere | | 76 | 22 | 30 | 52 | 5 | 16 | 1 | 0 | 2 | 0 | 147 | 171 | 12.9 |
| LW | Chris Kreider | | 77 | 26 | 26 | 52 | -5 | 44 | 3 | 0 | 2 | 0 | 104 | 193 | 13.5 |
| RW | Jack Quinn | | 76 | 22 | 30 | 52 | -3 | 21 | 3 | 1 | 4 | 0 | 166 | 199 | 11.1 |
| LW | Jake Neighbours | | 75 | 23 | 29 | 52 | 4 | 17 | 5 | 1 | 3 | 0 | 140 | 166 | 13.9 |
| RW | Kevin Fiala | | 75 | 21 | 31 | 52 | 0 | 22 | 2 | 0 | 2 | 1 | 96 | 166 | 12.7 |
| C | Logan Brown | | 76 | 19 | 33 | 52 | 6 | 34 | 5 | 0 | 3 | 0 | 144 | 181 | 10.5 |
| RW | Louis Leblanc | | 76 | 20 | 32 | 52 | -10 | 24 | 1 | 0 | 4 | 0 | 84 | 141 | 14.2 |
| C | Nico Hischier | | 73 | 17 | 35 | 52 | 11 | 22 | 3 | 0 | 2 | 1 | 148 | 176 | 9.7 |
| RW | Quinton Byfield | | 76 | 20 | 32 | 52 | 0 | 40 | 2 | 0 | 4 | 1 | 165 | 212 | 9.4 |
| LW | Roby Jarventie | | 76 | 21 | 31 | 52 | 10 | 38 | 4 | 0 | 4 | 1 | 116 | 194 | 10.8 |
| RW | Sam Colangelo | | 76 | 27 | 25 | 52 | 30 | 40 | 2 | 0 | 6 | 0 | 116 | 160 | 16.9 |
| RW | Taylor Raddysh | | 77 | 28 | 24 | 52 | 16 | 12 | 1 | 0 | 5 | 0 | 132 | 185 | 15.1 |
| RW | Anthony Mantha | | 76 | 23 | 28 | 51 | 5 | 39 | 5 | 1 | 5 | 0 | 126 | 153 | 15.0 |
| C | Evgeny Kuznetsov | | 76 | 14 | 37 | 51 | -15 | 28 | 2 | 1 | 4 | 1 | 108 | 156 | 9.0 |
| C | Frederik Gauthier | | 75 | 23 | 28 | 51 | -9 | 4 | 1 | 0 | 1 | 1 | 145 | 201 | 11.4 |
| LW | Kasperi Kapanen | | 77 | 15 | 36 | 51 | 26 | 32 | 1 | 0 | 5 | 0 | 120 | 127 | 11.8 |
