Leaders | Players | Teams | Award Races
| Pos | Player | Team | GP | G | A | Pts | +/- | PIM | PP | SH | GW | GT | Hits | Shots | % |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C | Connor McDavid | | 82 | 25 | 27 | 52 | -17 | 4 | 3 | 2 | 4 | 0 | 74 | 196 | 12.8 |
| D | Danny DeKeyser | | 77 | 9 | 34 | 43 | 5 | 32 | 3 | 0 | 0 | 0 | 103 | 134 | 6.7 |
| C | Daultan Leveille | | 77 | 29 | 46 | 75 | -9 | 36 | 3 | 1 | 6 | 0 | 61 | 209 | 13.9 |
| D | Derek Forbort | | 82 | 10 | 37 | 47 | 36 | 27 | 3 | 0 | 2 | 0 | 201 | 178 | 5.6 |
| C | Derick Brassard | | 82 | 27 | 58 | 85 | 0 | 74 | 3 | 1 | 3 | 0 | 213 | 246 | 11.0 |
| D | Dominik Masin | | 82 | 9 | 27 | 36 | -11 | 85 | 3 | 0 | 4 | 0 | 109 | 171 | 5.3 |
| D | Duncan Siemens | | 82 | 15 | 33 | 48 | 10 | 94 | 3 | 1 | 3 | 1 | 148 | 192 | 7.8 |
| C | Dylan Larkin | | 80 | 22 | 41 | 63 | 1 | 36 | 3 | 1 | 3 | 0 | 141 | 185 | 11.9 |
| RW | Elias Pettersson | | 82 | 15 | 39 | 54 | 2 | 40 | 3 | 1 | 2 | 0 | 159 | 166 | 9.0 |
| D | Erik Johnson | | 79 | 10 | 21 | 31 | 4 | 62 | 3 | 0 | 3 | 0 | 153 | 136 | 7.4 |
| D | Filip Johansson | | 80 | 6 | 19 | 25 | -16 | 46 | 3 | 0 | 2 | 0 | 104 | 136 | 4.4 |
| RW | Ilya Mikheyev | | 79 | 24 | 36 | 60 | -3 | 34 | 3 | 0 | 5 | 3 | 160 | 202 | 11.9 |
| C | Jack Eichel | | 80 | 24 | 36 | 60 | -25 | 14 | 3 | 0 | 6 | 0 | 105 | 172 | 14.0 |
| LW | Jake Virtanen | | 81 | 16 | 30 | 46 | -19 | 104 | 3 | 0 | 4 | 1 | 124 | 184 | 8.7 |
| RW | Jakub Klepis | | 82 | 23 | 37 | 60 | -4 | 65 | 3 | 0 | 5 | 0 | 116 | 190 | 12.1 |
| D | Jakub Zboril | | 82 | 11 | 30 | 41 | 10 | 22 | 3 | 1 | 2 | 2 | 186 | 188 | 5.9 |
| D | Jarred Tinordi | | 82 | 10 | 25 | 35 | 2 | 62 | 3 | 0 | 3 | 0 | 189 | 198 | 5.1 |
| RW | Jeff Carter | | 82 | 18 | 27 | 45 | -42 | 24 | 3 | 0 | 1 | 0 | 95 | 173 | 10.4 |
| RW | Jesse Puljujarvi | | 81 | 25 | 47 | 72 | 6 | 28 | 3 | 1 | 4 | 0 | 216 | 207 | 12.1 |
| RW | Joe Basaraba | | 82 | 5 | 3 | 8 | -13 | 16 | 3 | 0 | 1 | 0 | 13 | 34 | 14.7 |
| D | Johnny Boychuk | | 72 | 7 | 23 | 30 | 1 | 178 | 3 | 0 | 2 | 1 | 166 | 121 | 5.8 |
| RW | Joshua Ho-Sang | | 78 | 21 | 56 | 77 | 12 | 111 | 3 | 0 | 2 | 0 | 93 | 178 | 11.8 |
| C | Justin Daniels | | 82 | 17 | 19 | 36 | 1 | 53 | 3 | 0 | 3 | 0 | 52 | 138 | 12.3 |
| RW | Klim Kostin | | 82 | 16 | 29 | 45 | -26 | 22 | 3 | 1 | 1 | 0 | 160 | 160 | 10.0 |
| RW | Liam Foudy | | 60 | 15 | 23 | 38 | 15 | 40 | 3 | 0 | 4 | 0 | 34 | 86 | 17.4 |
